Types of Sarcoma

Sarcomas are classified into two main categories:

  • Soft tissue sarcomas. Soft tissue includes muscles, fat, blood vessels, nerves, fibrous tissues, or deep tissues. Approximately 80% of Sarcoma’s begin in soft tissue.
  • Bone cancers. Osseous sarcomas start in the bone and are very rare.

There are more than 70 sarcoma subtypes and these subtypes help shape prognosis and progression.

Common Subtypes of Sarcomas

  • Angiosarcoma. Tumors much like blood or lymphatic vessels.
  • Chondrosarcoma. Tumors develop from cartilage cells.
  • Fibrosarcoma. Cancer of fibrous tissue.
  • Gastrointestinal stromal tumor (GIST). Sarcoma of the gastrointestinal tract and the extra-gastrointestinal tract.
  • Leiomyosarcoma. Tumors developed from smooth muscle in abdominal and pelvic organs and blood vessels.
  • Liposarcoma. Tumors developed from fat tissue.
  • Osteosarcoma. Cancer cells that form bone.
  • Pleomorphic sarcoma. Tumors occur in the limbs (often the legs) and may also occur in the abdomen.

2016 Selected Research on GIST

Understanding genetic breast cancer risk: Processing loci of the BRCA Gist Intelligent Tutoring System

CR Wolfe, VF Reyna, CL Widmer, EM Cedillos-Whynott… – Learning and Individual …, 2016
Abstract The BRCA Gist Intelligent Tutoring System helps women understand and make
decisions about genetic testing for breast cancer risk. BRCA Gist is guided by Fuzzy-Trace
Theory,(FTT) and built using AutoTutor LITE. It responds differently to participants


[HTML] Phosphorylated-insulin growth factor I receptor (p-IGF1R) and metalloproteinase-3 (MMP3) expression in advanced gastrointestinal stromal tumors (GIST). A GEIS 19 …

J Maurel, A López-Pousa, S Calabuig, S Bagué… – Clinical Sarcoma Research, 2016
Background Most GISTs have mutations in KIT or PDGFRA. Patients with advanced GIST
with KIT exon 9, PDGFRA mutation or WT for KIT and PDGFRA have a worse progression-
free survival (PFS) compared to patients with KIT exon 11 mutated tumors. We evaluated